Detalhe da pesquisa
1.
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.
Cell
; 153(6): 1327-39, 2013 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23746844
2.
Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Mol Cell
; 76(3): 485-499.e8, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495563
3.
Specialized interferon action in COVID-19.
Proc Natl Acad Sci U S A
; 119(11)2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217532
4.
Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients as a function of therapeutic transfusion and hydroxyurea treatment.
Haematologica
; 108(12): 3418-3432, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439373
5.
In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction.
Am J Hematol
; 98(7): 1017-1028, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36971592
6.
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity.
Genome Res
; 27(10): 1645-1657, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28904012
7.
Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature.
Allergy
; 78(2): 579-583, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36273270
8.
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX.
EMBO J
; 31(5): 1266-78, 2012 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22246181
9.
ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1.
Nucleic Acids Res
; 41(22): 10241-53, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24049075
10.
Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation.
Cell Death Differ
; 30(4): 952-965, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36681780
11.
In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction.
bioRxiv
; 2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36824724
12.
Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients, as a function of therapeutic transfusion and hydroxyurea treatment.
bioRxiv
; 2023 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37066337
13.
FAM193A is a positive regulator of p53 activity.
Cell Rep
; 42(3): 112230, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36897777
14.
Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway.
Cancer Res
; 83(15): 2543-2556, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205634
15.
Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome.
bioRxiv
; 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37461585
16.
Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition.
Sci Adv
; 9(26): eadg6218, 2023 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379383
17.
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Nat Metab
; 5(12): 2131-2147, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957387
18.
EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.
Neuro Oncol
; 25(12): 2287-2301, 2023 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37486991
19.
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.
Nat Genet
; 55(6): 1034-1047, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277650
20.
Multi-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology.
Sci Rep
; 12(1): 22505, 2022 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36577800